Emerging Technologies for Gut Microbiome Research
نویسندگان
چکیده
منابع مشابه
[Advanced technologies for the human gut microbiome analysis].
Analysis of the human gut microbiome, collective genomes of over 100 trillion cells of intestinal microbes which form the complex bacterial community, has recently become more practical due to remarkable advances in next-generation sequencing technologies (NGS). Several studies using NGS-based metagenomic approaches have been conducted to comprehensively analyze genes/functions and species comp...
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Autism spectrum disorder (ASD) is a serious neurodevelopmental disorder that affects one in 45 children in the United States, with a similarly striking prevalence in countries around the world. However, mechanisms underlying its etiology and manifestations remain poorly understood. Although ASD is diagnosed based on the presence and severity of impaired social communication and repetitive behav...
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Culture-independent approaches have driven the field of microbiome research and illuminated intricate relationships between the gut microbiota and human health. However, definitively associating phenotypes to specific strains or elucidating physiological interactions is challenging for metagenomic approaches. Recently a number of new approaches to gut microbiota cultivation have emerged through...
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It is increasingly clear that the human gut microbiome has great medical importance, and researchers are beginning to investigate its basic biology and to appreciate the challenges that it presents to medical science. Several striking new empirical results in this area are perplexing within the standard conceptual framework of biomedicine, and this highlights the need for new perspectives from ...
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Polycystic ovary syndrome (PCOS) is a complex endocrine disorder that affects 8-13% of women at reproductive age worldwide. This disorder is usually associated with menstrual disorders, infertility, obesity, and insulin resistance. The underlying cause of this syndrome is unknown, however in recent years, researchers have shown an association between intestinal microbiota alterations )dysbiosi...
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ژورنال
عنوان ژورنال: Trends in Microbiology
سال: 2016
ISSN: 0966-842X
DOI: 10.1016/j.tim.2016.06.008